On 5 May 2026, WHO was alerted of a cluster of unknown febrile illnesses with a high mortality rate in Mongbwalu and Rwampara Health Zones, Ituri Province. Following investigation by rapid response teams, the cause was confirmed to be Bundibugyo virus disease (BVD) due to Bundibugyo virus (Orthoebolavirus bundibugyoense) - a species of Ebola virus - on 15 May with 8/13 positive samples from Rwampara.
On 15 May 2026, the DRC declared its 17th Ebola outbreak, affecting Rwampara, Mongbwalu, and Bunia Health Zones. Uganda subsequently confirmed two imported cases. On 16 May 2026, WHO declared the outbreak a Public Health Emergency of International Concern (PHEIC).
As of 20 May 2026 (WHO press releaset):
WHO expects those numbers to keep increasing, given the amount of time the virus was circulating before the outbreak was detected.
Further cases:
Authorities are concerned about the risk of further spread due to population high mobility, insecurity, and the proximity of affected areas to Uganda and South Sudan through a porous border.
The D.R. Congo has experienced several Ebola outbreaks in recent years. The most recent outbreak, in the Kasai provinces (species Orthoebolavirus zairense), was declared over in December 2025. In Ituri Province specifically, Ebola disease due to Ebola virus (Orthoebolavirus zairense) was last documented during the 2018-2020 outbreak. Bundibugyo virus was first reported in 2007 in Bundibugyo district in Uganda during an outbreak. The most recent outbreak due to Bundibugyo virus was in 2012 in DRC.
WHO assesses the risk of the epidemic as high at the national and regional levels, and low at the global level (including Switzerland and EU/EEW).
The outbreak was first detected in a remote and conflict-affected area of the Democratic Republic of Congo. There are significant uncertainties to the true number of infected persons and geographic spread associated with this event at the present time. In addition, there is limited understanding of the epidemiological links with known or suspected cases.
People visiting affected areas in D.R. Congo and Uganda should follow these precautions:
General preventive measures:
Of note: there is currently no licensed vaccine or specific treatment against Ebola diseased caused by Bundibugyo virus. For humanitarian missions, consultation with a travel medicine specialist is recommended.
While in the outbreak area and for 21 days after leaving:
! In case of symptoms (during your stay in North-eastern D.R. Congo (province of Ituri, North Kivu, South Kivu) and /or Uganda, especially the affected area, or until 21 days after leaving) such as fever >38° C:
Swiss recommendation: Cases should be suspected (see case definition of FOPH) in persons with a history of stay in the last 21 days in North-eastern D.R. Congo (province of Ituri, North Kivu, South Kivu) and/or Uganda AND a high-risk exposure*; such cases should be reported to the Cantonal Physician and Swiss Federal Office of Public Health within 2 hours.
*High-risk exposure includes participation in local funerals; contact with a sick patient at home, during transport, or in a healthcare facility; or attendance at a local healthcare facility for care.
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